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Test Category: Specialist Biochemistry

Investigation Name:Cobalt- Urine

Alias or Abbreviation:Urine Co, urine cobalt to creatinine ratio

Accreditation:UKAS ISO15189:2022 Accredited test: On scope

Intro:

Cobalt is a component of cyanocobalamin (vitamin B12 ) and as such is an essential element. The metal is mainly used to make high temperature high strength alloys and is also used in the semi-conductor industry. Di-cobalt edentate is used in the treatment of cyanide poisoning.
Chronic exposure to inorganic cobalt may be associated with cardiomyopathy.
Measurement of cobalt in urine is the investigation of choice for the monitoring of occupational exposure.

Pathology Laboratory:Trace Elements Laboratory

Requestable Seperately?Yes

Units: nmol/mmol creatinine

Minimum Sample Volume:2 mL urine

Expected Turnaround Time: 7 working days.
Urgent analysis where clinically indicated may be arranged directly with the laboratory.

Test Code:UCO

Sample Type:

Spot urine collected into a plain white -top universal container

Complex Reference Range:< 2 nmol/mmol creatinine

Referred to Another Laboratory?No

Storage Requirements:Store at 4 °C prior to dispatch

Posting Address / Requirements:Ambient temperature, 1st Class post.
Sandwell Health Campus,
Pathology Department,
Specialist Chemistry,
Lyndon, B71 4HJ

NPEX / PDF Reporting Available:Yes

EQA Scheme:UK NEQAS for Trace Elements

Further information:For occupational monitoring, a spot urine collected end of shift, end of working week is recommended.
We are a designated Supra-Regional Assay Service (SAS) Laboratory for Trace Elements.

Lead Contact Details:Dr Nicola Barlow, Consultant Clinical Scientist,
SAS Director Trace Elements Laboratory
Email: nicola.barlow1@nhs.net

Email Address For Chasing Results:rwh-tr.bcpsspecialistchemistryenquiries@nhs.net

Methodology:Inductively coupled plasma mass spectrometry

Site Sample Tested:Sandwell Health Campus

Cost:Please email: bcpspathology.info@nhs.net for further details

Contact Number:Tel: 0121 507 5162